Review: Effects of High-Protein Diets on Glycemic Control, Insulin Resistance, and Blood Pressure in Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/31466731/ A systematic review and meta-analysis (PMID: 31466731) explored how high-protein diets (HPDs) affect glycemic control, insulin resistance, and blood pressure in individuals with type 2 diabetes. Here's a breakdown of the key findings: Methodology - The review included nine randomized controlled trials with 418 participants. - Protein intake in intervention groups ranged from 25–32% of total energy, compared to 15–20% in control groups. - Study durations varied from 4 to 24 weeks, with a median of 12 weeks. - Outcomes analyzed included fasting glucose, HbA1c (a marker of long-term blood glucose), and blood pressure. Key Results Glycemic Control: - High-protein diets significantly reduced HbA1c levels compared to standard-protein diets. This suggests improved long-term glycemic management. - Fasting blood glucose levels showed modest reductions, though the results varied between studies. Insulin Resistance: - Improvements in insulin sensitivity were observed, particularly with diets rich in animal-derived protein sources. This was likely influenced by the role of branched-chain amino acids (e.g., leucine) in enhancing glucose metabolism. Blood Pressure: - Systolic and diastolic blood pressures were slightly reduced on high-protein diets, though the effects were not as pronounced as those on glycemic parameters. Heterogeneity and Limitations - Significant variability in study designs and protein sources made direct comparisons challenging. - Most trials were short-term, leaving questions about sustainability and long-term safety unanswered. Strengths of High-Protein Diets - They offer a potential non-pharmacological strategy to improve glycemic control in type 2 diabetes. - May also promote satiety, aiding weight management, which is critical for diabetes care.

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So it’s been a few weeks since I started the “classic physique” program with double dynamic progression and my new meal plan and here’s what has happened to me: -I’ve lost a few pounds and I’m a bit leaner. -Suits are tighter around my neck, lats, quads, arms. -I don’t feel depleted after my training sessions. Although my muscles are fried, my overall stamina remains high. -I’ve been getting complements and asked if I have a show coming up. Clearly they can see the changes in my body. That’s all for now! I hope no one here is stepping on stage next to me anytime soon lol. Thanks @Darian Bates !!

When choosing a protein powder, one of the most important things to look at is the calorie-to-protein ratio. This tells you how much of the powder's calories actually come from protein versus carbs or fat. For most people, a good benchmark is a 1:4 to 1:5 ratio. That means for every 100 calories, you should get 20 to 25 grams of protein. If the ratio is higher, like 1:2 or worse, it means there are a lot of extra calories coming from carbs or fats. Powders like that might work for people needing a calorie surplus, but for general use, they’re not ideal and I would prefer to be getting those extra fats and carbs from other food sources. Look for powders that keep carbs and fats low—under 2 grams of fat and 3 grams of carbs per 25 grams of protein is a good target. Whey isolates usually have better calorie-to-protein ratios than concentrates or plant-based proteins.

What context would one need to use Exemestane instead of anastrozole ? Thanks!