I have nothing against automation. In fact, I've created a whole PPC system that surrounds automation. I just don't believe in automating 100% of it. There or tons of PPC software out there that does this.
The problem is there is no Strategy in the PPC outside of good PPC practices (bidding, targeting, negating, etc).
To be truly successful on Amazon, you need top organic ranks. This leads to visibility and ultimately sales. PPC is a visibility lever. You need a Strategy to know which Keyword lever to pull.
The 100% automated PPC software only has your PPC data. Without the organic rank data, you're missing the Strategy.
You are running your PPC blind.