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129 contributions to KetoforCancer
What else in addition to Seyfried's protocol?
I had reached out to chat with the beloved Pablo Kelly, may he rest in peace. Unfortunately, I did not get to speak with him. I was eager to hear from him what else he did in addition to Dr. Seyfried's protocol. I am particularly wondering if the RGCC/Onconomics test/supplements were part of his journey. It is astounding to me and hope-instilling as well, to see that he was able to prolong his life this long. Thanks for any and all info that I might learn from his journey.
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10 pass Ozone Therapy and Mitochondrial Health - Pub Med
Ozone high dose therapy (OHT) improves mitochondrial bioenergetics in peripheral blood mononuclear cells. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301618/ Conclusion: The worldwide increasing number of people with chronic diseases is pushing conventional therapy to its limits. The described multi-pass Major AutoHaemo Therapy has been used worldwide in many practices for years quite succesfully. So far, there has been no detailed explanation for the health-promoting properties of OHT. The results of the presented studies have shown that OHT can modulate mitochondrial functions. These studies lay the foundation for the further development of OHT as a safe and reliable method in combating a variety of chronic diseases in an area of precision medicine.
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New comment 1h ago
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@William Buckley what is an 11 pass?
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@William Buckley thanks
What can inhibit Glutamine?
FROM CHAT GPT: Glutamine inhibition is often targeted in cancer therapy or metabolic research to restrict glutamine's role in cellular processes, especially since many tumors are glutamine-dependent. Here are some common approaches and compounds used for glutamine inhibition: 1. Glutaminase (GLS) Inhibitors: Glutaminase is an enzyme that converts glutamine into glutamate, a key step in glutamine metabolism. Inhibiting glutaminase can reduce glutamine availability for cell growth, especially in cancer cells. - CB-839 (Telaglenastat): One of the most well-known glutaminase inhibitors used in clinical trials for cancer therapy. - BPTES: An early inhibitor of GLS, although less potent than CB-839. 2. Glutamine Analogues: These are structural analogs of glutamine that can compete with glutamine for uptake and utilization in cells. - DON (6-Diazo-5-oxo-L-norleucine): A classic glutamine analog that inhibits multiple enzymes involved in glutamine metabolism. - Azaserine: Another glutamine analog that inhibits enzymes utilizing glutamine, particularly in nucleotide synthesis. 3. ASCT2 (SLC1A5) Inhibitors: ASCT2 is a glutamine transporter that facilitates the uptake of glutamine into cells. Blocking this transporter can limit glutamine's availability inside the cell. - V-9302: A small-molecule inhibitor targeting ASCT2, reducing glutamine uptake. 4. mTOR Inhibitors: Since glutamine can activate the mTOR pathway, which is crucial for cell growth and proliferation, mTOR inhibitors can indirectly affect glutamine metabolism. - Rapamycin (Sirolimus): An mTOR inhibitor that can be used to suppress the glutamine-driven mTOR signaling cascade. 5. GLUD (Glutamate Dehydrogenase) Inhibitors: GLUD converts glutamate (derived from glutamine) into α-ketoglutarate for use in the tricarboxylic acid (TCA) cycle. Inhibiting GLUD can reduce the energy and biosynthetic precursors provided by glutamine metabolism. 6. Inhibition of Amino Acid Synthesis Pathways:
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New comment 2h ago
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Wow! Thanks for sharing!
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@Stuart Briscoe ah yes! Thanks for the reminder!
Has Anyone Followed the Paleolithic Ketogenic Diet for 6 Months or More?
As individuals managing a metabolic disease, we often face dilemmas when choosing what to eat. Dairy or no dairy, this plant or that plant, this meat or that meat. I know there is no perfect answer and not all of us can depend on studies as it takes a special skill to decipher real studies from the biases in studies funded by big food and big pharma. I’d like to share my quick story about several detours in my diet journey: 1. Initially, I followed a clean diet of mostly plants, fish, eggs, grain, and other whole foods (e.g., cruciferous veggies, nuts, avocados, berries, salmon, fermented soy, kefir, wheat bread, etc). 2. After developing the metabolic disease, I changed to a ketogenic diet, it’s only been a few months. 3. Recently, I found the Paleolithic Ketogenic Diet (PKD), focusing on four-legged animal meat, animal fat, and organ meat. No dairy, no plants, no grain, no vegetable oils, no fish, no eggs. Having been on PKD for just a week, I've been feeling good, but of course, it’s subjective. Hence my question. I'd love to hear from anyone who has followed PKD for 6 months or longer. I would appreciate your experience and insights. I would also appreciate an expert comment from @Johnny Rockermeier if you will. Thank you
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New comment 2h ago
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A few days ago I went on YouTube to find some PKD guidance, and could not find anything useful. Might you have a link to some useful PKD guidance? I am reacting poorly to most foods, a bloat so big that I'm always looking pregnant,.... I also have an issue with peristalsis, which compounds my digestive issues, as I am unable to pass all the accumulated gas. Only by getting on the table and administering a colonic (because an enema doesn't work for me), does the accumulated air / gas move out from my body. (I am also unable to move poop out, and must get on the colonic table twice a day to get some poop out) I heard of PKD and thought of trying it, they will wait until I have more clarity about how this works.
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