Preliminary Don study analysis regarding administration
EDIT: If you ARE currently taking DON, please let us know in the comments how you do it, regarding administration timing and type! So I am currently skimming thorugh a bunch of don papers, of special interest to you guys are probably the following questions, I added some answers that might me valid 1) How to administer? It seems that it can be administered orally, intravenously and subcutaneously 2) Side effects? The study effects are predominantly nausea and vomiting 3) Dosing, in humans? In Den Staceys Case, dosing was 0,2-1,3 mg / kg, he did it orally. But no mentioning of a single dose or multiple doses, if it was ingested within a capsule to slow digestion 4) PEAK PLASMA LEVELS!! This is the question: When, after ingestion, will the peak occur? When will be the most don be in your system, to maximize efficacy, when in hbot? It seems that measuring this is EXTREMELY difficult and your doctor will to 99% not be able to do that, to measure that. And the half live seems to be quite variable e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575731/ "between 2.5 and 11.7 hours." (But in general it is only a few hours), maybe splitting the dose up into 2 parts is more beneficial, to ensure a high blood level. In general, subq (injection into belly fat for example) is slower than orally and iv would be the fastest. For the latter you will need a professional, also for subq yourself probably! Because in these cases it has to be dissolved and adminstered with professional care and knowledge. The researchers of this study talk about the difficulty in measuring don, inventing a new technique to do it, and giving data on intravenous injection: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357560/ In the graph shown, peak plasma levels were already at 0,25 hours (!), so 15 minutes about 5,6 , 5,8. They probably were pretty surprised by this, otherwise they would have set the measuring intervals way shorter. Meaning, that the very peak could already have been after 5 minutes :-p