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Peak Physique

Public • 72 • $30/m

7 contributions to Peak Physique
Lifting program
How do we get to the part of building the workout program?
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New comment 2d ago
2 likes • 2d
@Rodolfo Ayala gonna take a while pal people need to like your content so you can lvl up here’s a like for you :) I’m in the same ship 🛳️
Acne – P53 Expression
https://pubmed.ncbi.nlm.nih.gov/28927457/ This review suggests that the protein p53, known as the "guardian of the genome," plays a central role in the effectiveness of all anti-acne treatments. Here’s a breakdown: 1. p53 Activation by Anti-Acne Therapies: The treatments commonly used for acne appear to work by increasing the expression or activity of p53. Each type of treatment does this through different mechanisms: 2. Role of p53 in Acne Treatment: 3. Implications for Research Models: The review criticizes the use of p53-inactivated sebocyte cultures (cells that don't express p53) for acne research, as these models might not accurately represent how anti-acne treatments work, given p53's central role in their mechanisms. In essence, this review proposes that by upregulating p53, various anti-acne therapies achieve a common therapeutic effect—helping control the factors that lead to acne, such as excess oil production and inflammation.
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New comment 10d ago
1 like • 11d
This sounds interesting, can you explain it in Christian language for us regular folks… As understod by up regulating p53 you can aid on acne issues ? And if so there is any natural way to do this like suplements etc
0 likes • 10d
@Darian Bates thank you 🙏
What's Your Go-To Off-Season and Prep Cycle?
I’m interested in hearing about everyone’s favorite cycles for both off-season and prep. Also, how do you integrate peptides, exosomes, or stem cells into your stack? My Current Stack: Off-Season: - Base Cycle: Testosterone + Primobolan + NPP - Peptide Additions: Tesamorelin + Ipamorelin + BPC-157 Prep/Cutting: - Base Cycle: Testosterone + Primobolan + Proviron - Peptide Additions: IGF-1 LR3 + MOTS-C + SS-31 Would love to hear your thoughts and any unique combinations you’ve tried!
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New comment 15d ago
0 likes • 18d
@Darian Bates I use the t2 3,5 200mg when I’m down to 10%…. I’ve done it with and without just to try, to be honest it did help to dig down the without much cardio, again I was bigger this time …. So it might as well not do much I do bloods after I come off and thyroid function is always on point on te higher end ….. I know dbol is demonised now days…. Somehow I feel great on that small dose gives the kick before the gym and speed recovery after… anavar does the same but it kind a blunts my appetite… Regarding estrogen I never used an Ai til now that my test is up to 500mg per week …. What would be the solution to not use Ai …. Lower testosterone and up the dht derivatives? I only use low test in a cutting phase and I don’t like the feeling, I feel to dry and I have to much strength and yes estrogen stays on check ….being on 400 masteron and my weighs start to shoot up ⬆️ scary because I don’t want to tear anything even I have the strength I gradually go up on weights …. I don’t know 🤷‍♂️ how else to manage estrogen if I’m going to be on an androgen cicle …. Appreciate the feedback thank you 🙏
0 likes • 17d
@Darian Bates thank you 😊 and regarding the t3 I didn’t use cytomel it’s a suplement t2 3,5-Diiodothyronine you can find it in any supplement store at least in Europe… but got your point only use it if you’re low on to begin with …
What PEDs should I be researching
To preface this, I am 20, been training for 4 years, 85kg around 18% bf. I'm pretty well built for a natural physique but I'm considering my first cycle but not too sure what to look into and want to narrow my search. I'm looking to significantly cut down my bodyfat at least by the end of the year if possible. Cheers
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New comment 21d ago
0 likes • 21d
🤔 how good is your schedule, terms of food rest and training.. technique executing exercises.. do you know know to manage your macros, micros, supplements…. If you don’t have all of this on point,,. Gear won’t do much, you won’t be taking full advantage of the benefits and you’ll just covering up the lack of what I’ve mention above. Adherence to the routine etc. The boss up there 👆 told you to to start with non adrogenic compounds, same applies to the they will enhance what you are already doing depending on how good is this and your genes 🧬 you’ll get some results or others.
Next Coffee Hour
Hey Fam Please vote for which time suits you best for our next coffee hour/ Q&A call (If you vote, please make sure that you attend)
Poll
18 members have voted
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New comment 21d ago
0 likes • 21d
umm 🤔 are this American 🇺🇸 times or from where ?
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Anderson Lopez
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15points to level up
@anderson-lopez-2706
Looking expand my knowledge

Active 2d ago
Joined Oct 17, 2024
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